![]() ![]() When injected into a vein, the effects are most intense and are felt within a minute. When taken by mouth, the effects come on gradually, and are usually felt in about 10 to 20 minutes. The speed and intensity of the effects of opioids vary depending on how the drugs are taken. With higher doses, these effects are more intense and last longer. They may also produce euphoria, drowsiness, relaxation, difficulty concentrating, constricted pupils, a slight decrease in breathing rate, nausea, vomiting, constipation, loss of appetite and sweating. Low doses of opioids decrease the sensation of pain and the emotional response to pain. whether you’ve taken any alcohol or other drugs.whether you have certain pre-existing medical or psychiatric conditions.your mood, expectations and environment.how you take them (e.g., by injection, orally).The way opioids affect you depends on many factors, including: Opioid misuse is the third leading cause of accidental death in Ontario. Between 20, the number of prescription opioids legally dispensed in Canada climbed almost 24 percent with more than 21.7 million prescriptions dispensed last year. ![]() Because of the risk of abuse, opioids are prescribed cautiously for chronic pain. Opioids are prescribed by physicians to people with acute or chronic pain resulting from disease, surgery or injury. Prescription opioids come in various forms.
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